Two decades of prenatal diagnosis in hemophilia A and B: a systematic review of global trends and current practices

2026

83

Neutrophil-Mediated Effects on Hemostasis and Thrombosis: Unraveling Their Complex Interaction in Thrombotic Events

2026

82

In silico design of a novel therapeutic multi-epitope vaccine against NSCLC: a reverse vaccinology approach

2026

81

Mild and Moderate Hemophilia A in Iran: A Clinical Spectrum and Molecular Insights from a Cohort of 110 Patients Including Novel F8 Variants

2025

80

Molecular diagnosis of inherited platelet disorders: a tale of two realities – advanced vs. resource-limited setting

2025

79

Genotyping R1336X and Eliminating the Pseudogene Amplification in Type 3 von Willebrand Disease Patients

2025

78

HR9 cell-penetrating peptide: An effective delivery approach of gene editing vectors for tumor treatment

2025

77

Advances in engineering immune–tumor microenvironments on-a-chip: integrative microfluidic platforms for immunotherapy and drug discovery

2025

76

Investigation of the Potency of KALA and REV Cell-Penetrating Peptides for In Vitro/In Vivo Delivery of an HPV Multiepitope DNA Construct

2025

75

Immunoinformatics Analysis of Potent Therapeutic Formulations for the Development of HIV-1 Nefmut-Carrying Engineered Exosomes

2025

74

Effective Plant-Derived Proteins and Peptides in Leukemia Treatment

2025

73

Antitumor Effects of HPV E7 and L1-E7 Multiepitope DNA Constructs Delivered by Synthetic and Arginine-Rich Cell Penetrating Peptides

2025

72

Minimum dataset for the development of the National Haemophilia Registry

2025

71

Relationship between mutations in severe hemophilia A and risk of inhibitor development: A large single-center study

2024

70

Differential Immunostimulatory Effects of EGFP and +36 GFP on Immune Cells

2024

69

Inhibition of HPV18 E6/E7 Protein-Expressing HeLa Cell Proliferation Using Optimized De Novo CRISPR/Cas9 Constructs Delivered by the LL-37 Peptide

2024

68

Engineered ClearColi™-derived outer membrane vesicles as functional carriers for development of HIV-1 therapeutic vaccine candidate

2024

67

Gynecological bleeding in women with congenital bleeding disorders: A comprehensive cohort from Iran

2024

66

Impact of low-dose alendronate therapy on target joints in hemophilia patients in a low-income country

2024

65

Genotype-phenotype analyses of Iranian patients with hemophilia B (Leyden-) and hemophilia B (Leyden+): A single-center study

2024

64

Molecular and clinical profile of rare bleeding disorders: A single-center retrospective study

2024

63

Natural Anticoagulant Protein Levels in Patients With Beta-Thalassemia Major: A Case-Control Study

2024

62

Falsely prolonged prothrombin time test in a patient with erythrocytosis: a case report

2024

61

Successful Expression of DNA-Based Vaccine Construct Encoding Human Papillomavirus Type 16 E7 Fused to Heat Shock Protein B1 in Eukaryotic Cells

2023

60

Comparison of Adjuvant Effects of Montanide ISA-720 and Heat Shock Protein 27 in Increasing Immunostimulatory Properties of HIV-1 Nef-Vif Fusion Protein Construct

2023

59

Evaluation of MALAT-1 and HOTAIR LncRNAs Expression Levels in Incidence of Hemophilia

2023

58

LL-37 antimicrobial peptide and heterologous prime-boost vaccination regimen significantly induce HIV-1 Nef-Vpr antigen- and virion-specific immune responses in mice

2023

57

Congenital Factor V Deficiency, Diagnosis, and Management

2023

56

Associations of multiple genetic variations with plasma levels of Von Willebrand Factor and clinical phenotype in Iranian patients with Von Willebrand disease type 1

2023

55

Bleeding disorder of unknown cause: Results from Iranian study

2023

54

Congenital Bleeding Disorders and COVID-19—A Systematic Literature Review

2023

53

Molecular basis of rare congenital bleeding disorders

2023

52

Protein S Deficiency with Two Novel PROS1 Gene Variants

2023

51

Different dendritic cells-based vaccine constructs influence HIV-1 antigen-specific immunological responses and cytokine generation in virion-exposed splenocytes

2022

50

Immunopotentiation by linking Hsp70 T-cell epitopes to Gag-Pol-Env-Nef-Rev multiepitope construct and increased IFN-gamma secretion in infected lymphocytes

2022

49

Immunological investigation of a multiepitope peptide vaccine candidate based on main proteins of SARS-CoV-2 pathogen

2022

48

Genotypes and phenotypes characterization of 17 Iranian patients with inherited factor X deficiency: identification of a novel mutation: Leu487Phe

2022

47

Combination of human papillomaviruses L1 and L2 multiepitope constructs protects mice against tumor cells.

2021

46

Genetic analysis of non-severe hemophilia A phenotype with A discrepancy between one-stage and chromogenic factor VIII activity assays

2021

45

Tailored prophylaxis in children with severe hemophilia: A four-year Iranian study

2021

44

Inhibitor development in patients with type 3 Von Willebrand disease, a comprehensive study on 99 Iranian patients.

2021

43

Challenges and concerns of patients with congenital bleeding disorders affected by coronavirus disease 2019

2021

42

Persistent hiccups in a patient with mild congenital factor V deficiency and COVID‐19; clinical and laboratory finding of a rare bleeding disorder

2021

41

Congenital combined bleeding disorders, a comprehensive study of a large number of Iranian patients

2021

40

Do congenital bleeding disorders have a protective effect against COVID-19? A prospective study

2021

39

Correlation of SARS-CoV-2 infection with hepatitis and liver disorders

2021

38

Treatment of hepatitis C virus infection with direct-acting antiviral agent-based regimens in Iranian patients with hereditary bleeding disorders

2021

37

HIV-1 Accessory Proteins: Which one is Potentially Effective in Diagnosis and Vaccine Development?

2021

36

Antimicrobial/ anticancer peptides: bioactive molecules and therapeutic agents

2021

35

The next generation of HCV vaccines: a focus on novel adjuvant development

2021

34

In silico design and in vitro expression of novel multiepitope DNA constructs based on HIV-1 proteins and Hsp70 T-cell epitopes

2021

33

Expression of a novel HIV-1 Gag-Pol-Env-Nef-Rev multi-epitope construct in Escherichia coli

2021

32

Detection of Anti-IgGs against Heat Shock Proteins 27 and 20, HP91 Peptide, and HIV-1 Polypeptides in HIV-Positive and Negative Patients

2020

31

Pharmaceutical approaches for treatment of hepatitis C virus

2020

30

Small interfering RNAs and their delivery systems: A novel powerful tool for the potential treatment of HIV infections

2020

29

Molecular Study of Occult Hepatitis C Infection among Iranian Hemophilia Patients Treated with Direct-acting Antiviral Agents

2020

28

Impact of Blood Transfusion on the Prevalence of HHpgV-1, HPgV-1, and B19V Among Iranian HCV-infected Patients With Hemophilia

2020

27

B1 protein: a novel cell penetrating protein for in vitro and in vivo delivery of HIV-1 multi-epitope DNA constructs

2020

26

Genotyping of intron 1 and 22 inversion of factor VIII gene using IS-PCR in Kurdish patients of Iraq

2020

25

Human platelet antigens polymorphisms; association to the development of liver fibrosis in patients with chronic hepatitis C

2020

24

Design of novel multiepitope constructs based peptide vaccine against the structural S, N and M proteins of human COVID-19 using immunoinformatics analysis

2020

23

An overview of in silico vaccine design against different pathogens and cancer

2020

22

Development of HPV16,18,31,45 E5 and E7 peptides-based vaccines predicted by immunoinformatics tools

2020

21

Development of multiepitope therapeutic vaccines against the most prevalent high-risk human papillomaviruses

2020

20

Gastrointestinal bleeding in a newborn infant with congenital factor X deficiency and COVID‐19—A common clinical feature between a rare disorder and a new, common infection.

2020

19

Patients with congenital bleeding disorders appear to be less severely affected by SARS-CoV-2: is inherited hypocoagulability overcoming acquired hypercoagulability of rare coagulation factor deficiencies besides hemophilia

2020

18

First Report of Prevalence of Blood-Borne Viruses (HBV, HCV, HIV, HTLV-1 and Parvovirus B19) Among Hemophilia Patients in Afghanistan.

2019

17

Acute changes in cardiac function by direct acting antiviral therapy for hepatitis C-infected patients with thalassemia.

2019

16

Heat shock proteins in infection

2019

15

Heat-shock proteins in diagnosis and treatment: an overview of different biochemical and immunological functions

2019

14

Anti-viral effects of super positively charged mutant of green fluorescent protein

2019

13

Modified DCs and MSCs with HPV E7 antigen and small Hsps: Which one is the most potent strategy for eradication of tumors?

2019

12

Analysis of long non-coding RNA expression in hemophilia A patients

2019

11

Inflammatory and immune response genes: A genetic analysis of inhibitor development in Iranian hemophilia A patients

2019

10

In silico/In vivo analysis of high-risk papillomavirus L1 and L2 conserved sequences for development of cross-subtype prophylactic vaccine.

2019

9

Expression of the Neuron-Related Genes in hNGF-β-Treated PC12 Cells

2018

8

Polymorphisms in the TGF-β1 (rs1982037) and IL-2 (rs2069762, rs4833248) genes are not associated with inhibitor development in Iranian patients with hemophilia A

2018

7

Polymorphism analysis of the CTLA-4 (rs231775) gene as a marker of inhibitor development in Iranian patients with hemophilia A

2018

6

Detection of Occult Hepatitis B Virus Among Iranian HCV-Infected patients with Hemophilia Treated with Direct-Acting Antiviral Agents

2018

5

Prediction of cross-clade HIV-1 T-cell epitopes using immunoinformatics analysis

2018

4

Investigating the IGSF2 and TNFα Genes Polymorphism and the Risk of Inhibitor Development in Patients with Hemophilia A

2017

3

Recommendations for the Clinical Management of Hepatitis C in Iran: A Consensus-Based National Guideline.

2016

2

Physicochemical properties of polymers: An important system to overcome the cell barriers in gene transfection.

2015

1

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